New methods can help study the phenomenon of turbulence

In his doctoral thesis, Michael Roop develops numerical methods that allow finding physically reliable approximate solutions ...
eLife

Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

Conservation levels of gene expression abundance ratios are globally coordinated in cells, and cellular state changes under such biologically relevant stoichiometric constraints are readable as ...
eLife

Gene specificity landscapes for comparative transcriptomic analysis across tissues, cell types, and species

This important study advances a new computational approach to measure and visualize gene expression specificity across different tissues and cell types. The framework is potentially helpful for ...
AHA/ASA Journals

Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...