BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

Even women who felt well before pregnancy may begin to notice symptoms around 28 to 30 weeks, when the cardiovascular system reaches its peak workload.

Researchers at the University of California, Irvine have successfully performed preclinical laboratory testing of a replacement heart valve intended for toddlers and young children with congenital ...

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease, ...

(BPT) - A newborn's heart will grow roughly 15 times larger in volume by the time adulthood is reached — a remarkable transformation that presents an extraordinary challenge for pediatric heart ...

A congenital heart defect is a condition you’re born with. Types of heart defects vary in severity — with some, you’ll need surgery as a child, while others don’t need treatment until later in life or ...