We collected a unique pair of microRNA sequencing data sets for the same set of tumor samples; one data set was collected with and the other without uniform handling and balanced design. The former ...

The rapid evolution of mass spectrometry (MS) has transformed biological research, yet the reliability of these insights depends entirely on the rigor of the applied proteomics statistics.

While conventional magnetic resonance imaging (MRI) is measured in arbitrary intensity units, much work has centered on the development of normalization procedures. In this talk, we propose a simple, ...

Methods for depth normalization have been assessed primarily with simulated data or cell-line–mixture data. There is a pressing need for benchmark data enabling a more realistic and objective ...