A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational chemistry, is not unlike using the Rosetta Stone to unlock the secrets of ancient ...

Researchers have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein ...

Researchers combined AI simulations with NMR data to capture fleeting structures of intrinsically disordered proteins, offering new insight into protein misfolding linked to neurodegenerative diseases ...

The researchers matched the 3D shapes to the structures of proteins whose functions are already known. Because the structure of a protein directly contributes to its biological function, their study ...

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

A DGIST research team led by Prof. Yoo Wookyung (Department of Brain Sciences) and Prof. Kim Jin Hae (Department of New Biology) developed an innovative analytical technology in collaboration with a ...

A new study suggests Alzheimer’s disease may be detectable through subtle shape changes in proteins found in the blood.