Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by enabling improved scalability and purity.

What is it? As the name suggests, nonribosomal peptide synthesis (NRPS) generates polypeptides sans ribosome. The resultant peptides, generally short oligomers of two to perhaps 48 residues, are not ...

A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

In May, TheraCode acquired JPT Peptide Technologies, a wholly owned subsidiary of Jerini. JPT offers peptide-based products and services for vaccine development, immune monitoring, and peptide ...

Vapourtec's Peptide-Builder, a fully automated, high-throughput benchtop peptide synthesizer, has been designed to redefine solid-phase peptide synthesis (SPPS). Compact, efficient and intuitive, it ...

A peptide sequence that performs well at micromole scale may behave unpredictably at gram or kilogram scale. Coupling efficiency, acceptable with high reagent excess, can drop when equivalents are ...

The Peptide-ExplorerLT ™ is designed for scientists who need to optimize and explore linear peptide synthesis. The product is a high-spec flow chemistry system that uses continuous flow. The product ...

Amide Technologies has raised $16.5 million in venture capital to help commercialize its peptide production process. The process was developed from 2011 to 2017 in the lab of the Massachusetts ...

BERLIN, April 22, 2020 (GLOBE NEWSWIRE) -- JPT Peptide Technologies (JPT) announces the launch of ready-to-use peptide tools to study and profile the immune response towards SARS-CoV-2 infection. The ...

Synthetic peptides, generally less than 20 amino acids in length, are essential reagents for a wide range of studies and one of the fundamental tools of proteomics researchers. Applications include ...