First responders said no one was inside the home at the time of the explosion. No injuries have been reported.
Washington Gas crews were still working to restore service to many residents who said they are struggling to stay warm.
A gas line repair in Beltsville led to an explosion, seriously injuring one person and sparking a fire.
On Friday, a gas line ignited near the Beltsville area, sending a utility employee to the hospital. Now hundreds remain without service.
A worker who witnessed the explosion in Ypsilanti Township on Wednesday described what happened inside the building.